In this study, Macleaya cordata were stressed by PEG6000 simulating drought and mechanical damaging, and HPLC was used to detect the contents of protopine, allocryptopine, sanguinarine and chelerythrine. It was found that the contents of end products in Macleaya root such as sanguinarine and chelerythrine increased by 30% PEG6000 sximulating drought stressing and mechanical damaging. On the contrary, the contents of intermediate products such as protopine and allocryptopine reduced. Meanwhile, there was up-regulation in expression of synthetic genes DBOX and P6H in sanguinarine and chelerythri...
