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Apoptosis or Antiapoptosis? Interrupted Regulated Cell Death of Host Cells by Ascovirus Infection In Vitro

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成果类型:
期刊论文
作者:
Yu, Huan;Li, Jin-Rong;Xiao, Hua-Yan;Cao, Sheng-Kai;Chen, Bin;...
通讯作者:
Gong Chen<&wdkj&>Guo-Hua Huang
作者机构:
[Cao, Sheng-Kai; Li, Ni; Chen, Gong; Yu, Huan; Li, Jin-Rong; Huang, Guo-Hua; Xiao, Hua-Yan; Chen, Bin] Hunan Agr Univ, Hunan Prov Key Lab Biol & Control Plant Dis & Inse, Changsha, Hunan, Peoples R China.
[Cao, Sheng-Kai; Li, Ni; Chen, Gong; Yu, Huan; Li, Jin-Rong; Huang, Guo-Hua; Xiao, Hua-Yan; Chen, Bin] Hunan Agr Univ, Coll Plant Protect, Changsha, Hunan, Peoples R China.
通讯机构:
[Gong Chen; Guo-Hua Huang] H
Hunan Provincial Key Laboratory for Biology and Control of Plant Diseases and Insect Pests, Hunan Agricultural University, Changsha, Hunan, China<&wdkj&>College of Plant Protection, Hunan Agricultural University, Changsha, Hunan, China
语种:
英文
关键词:
regulated cell death;ascovirus;apoptosis;pyroptosis;Heliothis virescens ascovirus 3h
期刊:
MBIO
ISSN:
2150-7511
年:
2023
卷:
14
期:
1
页码:
e0311922
基金类别:
National Natural Science Foundation of China [32281340018, 32172408, CARS-23-C08]; China Agriculture Research System [2022-31]; Modern Agricultural Industrial Technology System of Hunan Province [2022-42]; [32070168]
机构署名:
本校为第一机构
院系归属:
植物保护学院
摘要:
Ascoviruses are insect-specific viruses thought to utilize the cellular apoptotic processes of host larvae to produce numerous virion-containing vesicles. In this study, we first determined the biochemical characteristics of ascovirus-infected, in vitro-cultured insect cells and the possible antiapoptotic capacity of ascovirus-infected insect cells. The results indicated that the ascovirus infection in the first 24h was different from the infection from 48h to the later infection stages. In the early infection stage, the Spodoptera exigua host ...

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