期刊论文

Liu, Gang;Fang, Jun

英文

Frontiers in Microbiology

1664-302X

2019

10

APR

643

10.3389/fmicb.2019.00643

National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31672457, 31772642]; National Key Research and Development Program of China [2016YFD0500504, 2016YFD0501201]; Ministry of Agricultural of the People's Republic of China [2015-Z64, 2016-X47]; Local Science and Technology Development Project Guided by The Central Government [YDZX20184300002303, 2018CT5002]; Hunan Provincial Science and Technology Department [2017NK2322, 2018TP1031, 2016NK2101, 2016WK2008, 2016TP2005, 2018WK4025]; China Postdoctoral Science FoundationChina Postdoctoral Science Foundation [2018M632963]; Double first-class construction project of Hunan Agricultural University [SYL201802003, YB2018007]

本校为第一且通讯机构

Bioactive peptides that target the gastrointestinal tract can strongly affect the health of animals and humans. This study aimed to evaluate the abilities of two peptides derived from egg albumin transferrin, IRW and IQW, to treat enteritis in a mouse model of Citrobacter rodentium-induced colitis by evaluating serum metabolomics and gut microbes. Forty-eight mice were randomly assigned to six groups: basal diet (CTRL), intragastric administration Citrobacter rodentium (CR), basal diet with 0.03%IRW (IRW), CR with 0.03% IRW (IRW+CR), basal diet...