版权说明 操作指南
首页 > 成果 > 详情

hnRNP K regulates mitochondrial apoptosis induced by porcine circovirus type 3 capsid protein

认领
导出
Link by DOI
反馈
分享
QQ微信 微博
成果类型:
期刊论文
作者:
He, Qing;Cao, Siyu;Yu, Wanting;Li, Zhoumian;Liu, Weijiao;...
通讯作者:
Wang, Naidong
作者机构:
[Liu, Weijiao; He, Qing; Li, Dantong; Zou, Yawen; Yu, Beilei; Zhan, Yang; Wu, Jing; Cao, Siyu; Li, Zhoumian; Jiang, You; Yang, Yi] Hunan Provincial Key Laboratory of Protein Engineering in Animal Vaccines, Laboratory of Functional Proteomics (LFP) & Research Center of Reverse Vaccinology (RCRV), College of Veterinary Medicine, Hunan Agricultural University, Changsha, China
[Yu, Wanting] College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang, Jiangxi, China
[Tian, Chuanwen] Key Laboratory of Animal Biosafety Risk Prevention and Control (North), P.R. China, Shanghai Veterinary Research Institute, Biosafety Research Center, Chinese Academy of Agricultural Sciences, Shanghai, China
[Wang, Naidong] Hunan Provincial Key Laboratory of Protein Engineering in Animal Vaccines, Laboratory of Functional Proteomics (LFP) & Research Center of Reverse Vaccinology (RCRV), College of Veterinary Medicine, Hunan Agricultural University, Changsha, China. Electronic address: naidongwang@hunau.edu.cn
通讯机构:
[Wang, Naidong] H
Hunan Provincial Key Laboratory of Protein Engineering in Animal Vaccines, Laboratory of Functional Proteomics (LFP) & Research Center of Reverse Vaccinology (RCRV), College of Veterinary Medicine, Hunan Agricultural University, Changsha, China. Electronic address:
语种:
英文
关键词:
Cap;HnRNP K;Mitochondrial apoptosis;Porcine circovirus type 3
期刊:
Veterinary Microbiology
ISSN:
0378-1135
年:
2025
卷:
306
页码:
110557
基金类别:
CRediT authorship contribution statement Jiang You: Validation. Wu Jing: Validation, Data curation. He Qing: Writing – original draft, Methodology, Investigation, Data curation. Yang Yi: Supervision, acquisition. Cao Siyu: Investigation, Data curation. Wang Naidong: Writing – review & editing, Supervision, Methodology, acquisition. Yu Wanting: Validation, Formal analysis. Zhan Yang: Supervision, acquisition. Yu Beilei: Resources. Zou Yawen: Software, Project administration. Li Zhoumian: Validation, Formal
机构署名:
本校为第一且通讯机构
院系归属:
动物医学院
摘要:
Porcine circovirus type 3 (PCV3) is a globally emerging circovirus affecting pigs and other animals. The capsid protein (Cap) is the sole structural protein of PCV, with a crucial role in virus evolution and pathogenesis. Through interactions with host factors, Cap enables viral entry, transport, and replication while modifying various cellular processes. Cap protein-induced apoptosis has important implications for viral pathogenesis, but remains poorly defined. Herein, we demonstrated for the first time that PCV3 Cap induced cell cycle arrest of PK-15 cells in S-phase and initiated apoptosis ...

反馈

验证码:
看不清楚,换一个
确定
取消

成果认领

标题:
用户 作者 通讯作者
请选择
请选择
确定
取消

提示

该栏目需要登录且有访问权限才可以访问

如果您有访问权限,请直接 登录访问

如果您没有访问权限,请联系管理员申请开通

管理员联系邮箱:yun@hnwdkj.com