期刊论文

中文

现代食品科技

1673-9078

2020

36

10

8-15

10.13982/j.mfst.1673-9078.2020.10.0219

国家现代农业产业技术体系(CARS-29-ZP-9) 湖南省教育厅科学研究项目(17C0768)。

本校为第一机构

本研究以SPF级SD大鼠为实验动物,探讨刺葡萄酒对高脂饲料喂养大鼠的降血脂作用及可能机制.结果 显示,刺葡萄酒能显著降低甘油三酯含量,低剂量刺葡萄酒能显著降低大鼠血清内总胆固醇至1.67 mmol/L (p＜0.05);中剂量刺葡萄酒处理能显著降低密度脂蛋白胆固醇含量(p＜0.01)并显著增加高密度脂蛋白胆固醇含量至0.97 mmol/L (p＜0.05).各剂量刺葡萄酒处理能显著增加大鼠血清内超氧化物歧化酶和谷丙转氨酶(p＜0.01)的活性,显著降低血清丙二醛的含量(p＜0.05).Q-PCR结果显示,刺葡萄酒可促进高脂饮食大鼠肝脏卵磷脂胆固醇脂酰转移酶(LCAT)(1.47倍)、丙二酰辅酶A脱羧酶(MCD)(2.21倍)、肉碱棕榈酰转移酶(CP...

In this study, SPF grade SD rats were used as experimental animals to study the hypolipidemic effects and possible mechanism of red wine made from V. didii. Foëx. The results showed that the content of triglyceride in the serum of rats was significantly reduced by V. didii. Foëx Wine, and the content of total cholesterol in the serum of rats was significantly reduced to 1.67 mmol/L under the low dose (p