期刊论文

Grey matter concentration revealed by voxel-based morphometry in individuals with cognitive vulnerability to depression

Zhang, X.

中文

中南大学学报(医学版)

1672-7347

2017

42

6

667-672

10.11817/j.issn.1672-7347.2017.06.012

国家自然科学基金（81501178）~~；

本校为其他机构

目的:探讨抑郁症认知易感者脑灰质密度的特征。方法:运用磁共振成像(MRI)技术采集30例抑郁症认知易感者及30例正常对照者的全脑解剖成像数据,应用基于体素的形态测量(voxel-based morphometry,VBM)方法分析比较两组研究对象全脑灰质密度的差异。结果:抑郁症认知易感者双侧脑岛、左侧小脑、右侧辅助运动区及左侧中央前回的灰质密度显著低于正常组(P

Objective: To explore the grey matter concentration in individuals with cognitive vulnerability to depression. Methods: Thirty individuals with cognitive vulnerability to depression and thirty age- And gender-matched healthy controls were enrolled in this study, and they were subjected to magnetic resonance imaging (MRI) examination. Hie grey matter concentration differences were compared between the two groups by using voxel-based morphometry (VBM) following MRI. Results: Individuals with cognitive vulnerability to depression showed significantly lower grey matter density in bilateral insular...