期刊论文

Liao, P

英文

Food and Chemical Toxicology

0278-6915

2023

177

113863

10.1016/j.fct.2023.113863

This research was supported by the Key projects of Guangxi Natural Science Foundation ( 2020GXNSFDA297002 ), Fujian Provincial Science and Technology Plan Project ( 2020T3029 ), Fujian Provincial Science and Technology Department and Chinese Academy of Sciences Supporting Project of STS Program ( 2021T3051 ), Zhanjiang science and technology planning project ( 2021A05025 ), local science and technology development fund project of the Central Committee of Guangxi Zhuang Autonomous Region (Gui ke ZY21195054 ), Guizhou Provincial Science and Technology Plan Project (Qian ke he cheng guo [2021] yi ban 037), Application and industrialization of scientific and technological achievements in Guizhou Province (Qian ke he cheng guo [2022] yi ban 002), the Jiangxi Technological Innovation Guidance Plan Project ( 20212BDH81024 ), the Key R&D Projects in Jiangxi Province ( 20212BBF63023 ), the National Natural Science Foundation of China ( 31960666 ).

本校为其他机构

Mycotoxins, especially deoxynivalenol (DON), are common contaminants of food and feed, which also has serious threaten to human health and livestock production. Moreover, DON severely impair intestinal epithelial barrier function. Therefore, it is necessary to investigate the mechanism of intestinal epithelial cell injury induced by DON. Here, intestinal porcine enterocyte cell (IPEC-J2) was incubated with 200 ng/ml or 2000 ng/ml DON for 6 h, then lncRNA sequencing, metabolomics and proteomics were applied. Combined with long coding transcripto...