An optimal macroporous adsorption resin was chosen to purify the carotenoid produced by Rhodotorula mucilaginosa.And its conditions of static adsorption and desorption were studied in this paper.The result show that DS-401 resin was of excellent adsorption and desorption performance to carotenoid.The optimal adsorption condition was pH6.0,25 ℃,1 h,adsorption rate was up to 80.58 %.The optimal desorption condition was 30 ℃,1 h while 100 % petroleum ether was taken as...