To explore the humoral immune responses in mice against Schistosoma japonicum（S.japonicum） elicited by immunization with synthetic peptides, a panel of four M13 phage-originated mimotopes of three S.japonicum vaccine antigens was synthesized. Enzyme-finked immunosorbant assay（ELISA） was used to evaluate these four synthetic peptides for their antigenicity. After the peptides were conjugated to keyhole limpet hemocyanin（KLH）, the conjugates were used to immunize Kunming mice. Mice sera were collected 2 weeks after the third immunization to...
