Resveratrol was extracted from grapevine by ethanol reflux extraction, and the quadratic regression equation y=-6.18639+0.1817x1-0.012371x2+0.12293x3+0.000273x1x2-0.000545x1x3-0.000164x2x3-0.001178x1-00004x2^2-0.002998x3^2(r=0,9361,P〈0.01) was obtained by selecting the ethanol concentration (x0, time for refluxing extraction (x2) and ratio of solvent to raw material (x3) as independent variables and the extraction rate of resveratrol as dependent variables. Then the extraction process was optimized using central composite design and ...