Retinol binding protein 4(RBP4), an important candidate gene for traits of sow litter size(LS), plays a key role in vitamin transportation on the maternal-fetal interface during swine pregnancy. Candidates of exonic single nucleotide polymorphisms(SNPs) in gene RBP4 were scanned through bioinformatics analysis, and SNP A1027 G, neighboring to Msp Ⅰ RFLP(SNP G1223C) with molecular marked was validated, and the correlation between LS traits and polymorphisms of RBP4 gene were further analyzed both on the population of Large White and Hun...