Dear Editor, Pepper (C. annuum L.) is an important vegetable crop worldwide [1], with remarkable diversity in morphology, nutrition, color, flavor, and yield. A great effort has been made to identify quantitative trait loci (QTLs) and genes that affect these traits [2, 3]. However, few effective combinatorial events in small population sizes have limited the mapping of high-confidence QTLs for markerassisted breeding (MAB) and map-based gene cloning. The combined multi-omics approach has provided powerful tools for the rapid mining of candidate genes for MAB and for improving our understanding...