Compound mutation of Trichosporon cutaneum with UV and diethyl sulfate(DES) was studied. The result indicated that when the UV lamp was 15W, the irradiation distance was 30 cm and the irradiation time was 60 s, the mutation strain of pi - 60 with 30.4% of oil content and 1. 135 4 g/100 mL of biomass could be selected. When the DES was applied to the strain pi -60, and the mutation strain (pi - 60 -70) with 35.7% of oil content and 1. 257 3 g/100 mL of biomass could be selected by treating for 70 miu with 1.0% DES. Compared with the original st...