Photoinhibiting via simultaneous photoabsorption and free-radical reaction for high-fidelity light-based bioprinting

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成果类型：

期刊论文

作者：

He, Ning;Wang, Xiaonan;Shi, Liyang;Li, Jing;Mo, Lan;...

通讯作者：

Chen, Feng;Han, XX

作者机构：

[He, Ning; Li, Jing; Mao, Yiqi; Han, Xiaoxiao; Zhu, Xiaolong; Zhu, Wei; Chen, Feng; Chen, F] Hunan Univ, Natl Engn Res Ctr High Efficiency Grinding, Changsha 410082, Peoples R China.

[He, Ning; Han, Xiaoxiao] Hunan Univ, State Key Lab Adv Design & Manufacture Vehicle Bod, Changsha 410082, Peoples R China.

[Wang, Xiaonan; Shi, Liyang] Hunan Univ, Coll Biol, Changsha 410082, Peoples R China.

[Mo, Lan] Hunan Agr Univ, Coll Food Sci & Technol, Changsha 410128, Peoples R China.

[Huang, Yuting; Liu, Hairong] Hunan Univ, Coll Mat Sci & Engn, Changsha 410082, Peoples R China.

通讯机构：

[Han, XX ; Chen, F] H

Hunan Univ, Natl Engn Res Ctr High Efficiency Grinding, Changsha 410082, Peoples R China.

Hunan Univ, State Key Lab Adv Design & Manufacture Vehicle Bod, Changsha 410082, Peoples R China.

语种：

英文

期刊：

Nature Communications

ISSN：

2041-1723

年：

2023

卷：

期：

页码：

3063

DOI：

10.1038/s41467-023-38838-2

基金类别：

National Natural Science Foundation of China [52075158]; National Natural Science Foundation of Hunan Province [2021JJ30109]; Innovative Platform and Talents Program of Hunan Province [2019RS1019]; Key R&D Program of Hunan Province [2020SK2093]; Postgraduate Scientific Research Innovation Project of Hunan Province [CX20220407]

机构署名：

本校为其他机构

院系归属：

食品科学技术学院

摘要：

Light-based 3D bioprinting is now employed widely to fabricate geometrically complex constructs for various biomedical applications. However, the inherent light scattering defect creates significant challenges in patterning dilute hydrogels to form high-fidelity structures with fine-scale features. Herein, we introduce a photoinhibiting approach that can effectively suppress the light scattering effect via a mechanism of simultaneous photoabsorption and free-radical reaction. This biocompatible approach significantly improves the printing resol...

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Photoinhibiting via simultaneous photoabsorption and free-radical reaction for high-fidelity light-based bioprinting

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