Reprogramming the fatty acid metabolism of Yarrowia lipolytica to produce the customized omega-6 polyunsaturated fatty acids

首页 > 成果 > 详情

认领

导出

Link by DOI

反馈

作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Wang, Jinpeng;Yu, Xiao;Wang, Kaifeng;Lin, Lu;Liu, Hu-Hu;...

通讯作者：

Ji, XJ

作者机构：

[Wang, Kaifeng; Lin, Lu; Ji, Xiao-Jun; Wang, Jinpeng; Yu, Xiao] Nanjing Tech Univ, Coll Biotechnol & Pharmaceut Engn, State Key Lab Mat Oriented Chem Engn, 30 South Puzhu Rd, Nanjing 211816, Peoples R China.

[Liu, Hu-Hu] Hunan Agr Univ, Coll Biosci & Biotechnol, 1 Nongda Rd, Changsha 410128, Peoples R China.

[Ledesma-Amaro, Rodrigo] Imperial Coll London, Dept Bioengn, London SW7 2AZ, England.

[Ledesma-Amaro, Rodrigo] Imperial Coll London, Imperial Coll Ctr Synthet Biol, London SW7 2AZ, England.

通讯机构：

[Ji, XJ ] N

Nanjing Tech Univ, Coll Biotechnol & Pharmaceut Engn, State Key Lab Mat Oriented Chem Engn, 30 South Puzhu Rd, Nanjing 211816, Peoples R China.

语种：

英文

关键词：

Arachidonic acid;Dihomo-gamma-linolenic acid;Gamma-linolenic acid;Omega-6 polyunsaturated fatty acids;Yarrowia lipolytica

期刊：

Bioresource Technology

ISSN：

0960-8524

年：

2023

卷：

383

页码：

129231

DOI：

10.1016/j.biortech.2023.129231

基金类别：

CRediT authorship contribution statement Jinpeng Wang: Conceptualization, Data curation, Methodology, Writing – original draft, Visualization. Xiao Yu: Data curation, Methodology. Kaifeng Wang: Formal analysis, Writing – review & editing. Lu Lin: Data curation, Visualization, Investigation. Hu-Hu Liu: Methodology, Investigation, Writing – review & editing. Rodrigo Ledesma-Amaro: Writing – review & editing. Xiao-Jun Ji: Conceptualization, Writing – review & editing, Project administration, acquisition.

机构署名：

本校为其他机构

院系归属：

生物科学技术学院

摘要：

Omega-6 polyunsaturated fatty acids (ω6-PUFAs), such as γ-linolenic acid (GLA), dihomo-γ-linolenic acid (DGLA) and arachidonic acid (ARA), are indispensable nutrients for human health. Harnessing the lipogenesis pathway of Yarrowia lipolytica creates a potential platform for producing customized ω6-PUFAs. This study explored the optimal biosynthetic pathways for customized production of ω6-PUFAs in Y. lipolytica via either the Δ6 pathway from Mortierella alpina or the Δ8 pathway from Isochrysis galbana. Subsequently, the proportion of ω...

反馈

产权有误：本人成果被他人认领

数据有误：数据基本信息有误

归属有误：成果的院系归属、机构署名归属有误

其他原因：

验证码：

看不清楚，换一个

确定

取消

成果认领

标题：

用户	作者	通讯作者	--
	请选择	请选择	--

确定

取消

Reprogramming the fatty acid metabolism of Yarrowia lipolytica to produce the customized omega-6 polyunsaturated fatty acids

反馈

成果认领

提示

该栏目需要登录且有访问权限才可以访问