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Effect of the Combination of Clostridium butyricum and Mycelium of Phellinus igniarius on Intestinal Microbiota and Serum Metabolites in DSS-Induced Colitis

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成果类型:
期刊论文
作者:
Zhao, Rou;Zhang, Qiaoyi;Huang, Ting;Tian, Yun;Guan, Guiping;...
通讯作者:
Lin, YS
作者机构:
[Lin, Yuanshan; Zhao, Rou; Lin, YS] Hunan Agr Univ, Coll Biosci & Biotechnol, Changsha 410128, Peoples R China.
[Tian, Yun; Zhang, Qiaoyi; Huang, Ting; Guan, Guiping] Agr Bioengn Inst, Changsha 410128, Peoples R China.
通讯机构:
[Lin, YS ] H
Hunan Agr Univ, Coll Biosci & Biotechnol, Changsha 410128, Peoples R China.
语种:
英文
关键词:
Clostridium butyricum;mycelium of Phellinus igniarius;colitis;intestinal flora;serum metabolome
期刊:
Nutrients
ISSN:
2072-6643
年:
2024
卷:
16
期:
1
页码:
153-
基金类别:
Conceptualization, Y.L. and Y.T.; data curation, R.Z.; formal analysis, Q.Z. and G.G.; funding acquisition, Y.L.; software, Q.Z. and T.H.; writing—original draft, R.Z. All authors have read and agreed to the published version of the manuscript. This study was supported by the Hunan Provincial Department of Education, Hunan Provincial High Efficiency Innovation Platform Open Fund Project (19k045).
机构署名:
本校为第一且通讯机构
院系归属:
生物科学技术学院
摘要:
Clostridium butyricum (CB) and Phellinus igniarius (PI) have anti-inflammatory, immune regulation, anti-tumor, and other functions. This study aimed to explore the therapeutic effect of CB and mycelium of PI (MPI) alone and in combination on colitis mice induced by dextran sodium sulfate (DSS). Mice were randomly assigned to five groups: (1) control (CTRL), (2) DSS, (3) CB, (4) MPI, and (5) CB + MPI (CON). The weight of the mice was recorded daily during the experiment, and the length of the colon was measured on the last day of the experiment....

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