期刊论文

Dai, ER;Wang, YL

英文

BMC Genomic Data

2730-6844

2023

24

1

1-10

10.1186/s12863-023-01133-6

This work was supported by grants from Immune profiling of COVID-19 patients based on Mass Cytometry (202230714010258). The funding body had no role in the design of the study and collection, analysis, and interpretation of data and in writing the manuscript.

本校为其他机构

Evidence shows that genetic factors play important roles in the severity of coronavirus disease 2019 (COVID-19). Sulfatase modifying factor 1 (SUMF1) gene is involved in alveolar damage and systemic inflammatory response. Therefore, we speculate that it may play a key role in COVID-19. We found that rs794185 was significantly associated with COVID-19 severity in Chinese population, under the additive model after adjusting for gender and age (for C allele = 0.62, 95% CI = 0.44–0.88, P = 0.0073, logistic regression). And this association w...