Dynamics, e. g. distribution, accumulation and transfer, of ciprofloxacin (CPFX) in water, sediments and biota in a simulated micro-cosmic aquatic system was studied with HPLC. Results show that once CPFX was released into water body, a portion of it was assimilated by aquatic organisms and a portion deposited into the sediments. Concentration of CPFX in water, sediments and biota varied with the time. The concentration of CPFX decreased rapidly in the water, from 500.00 to 15.30 μg · L -1 within one day, but increased in the sediment up to 3...