Enhancement of edeine production in Brevibacillus brevis X23 via in situ promoter engineering

首页 > 成果 > 详情

认领

导出

Link by DOI

反馈

作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Liu, Qingshu;Zhang, Liang;Wang, Yunsheng;Zhang, Cuiyang;Liu, Tianbo;...

通讯作者：

Dingjun Li<&wdkj&>Wu Chen

作者机构：

[Zhang, Liang; Wang, Yunsheng; Liu, Tianbo; Liu, Qingshu; Dai, Liangying; Chen, Wu; Li, Dingjun] Hunan Agr Univ, Coll Plant Protect, Changsha 410128, Peoples R China.

[Liu, Qingshu; Du, Jie; Tang, Ying; Long, Qingshan; Guo, Zhaohui; Duan, Caichen; Zhang, Cuiyang] Hunan Inst Microbiol, Hunan Prov Engn Res Ctr Agr Microbiol Applicat, Changsha 410009, Peoples R China.

[Zhang, Liang; Liu, Aiyu] Hunan Agr Univ, Coll Agron, Changsha 410128, Peoples R China.

[Bian, Xiaoying] Shandong Univ, Helmholtz Inst Biotechnol, Helmholtz Int Lab Antiinfect, State Key Lab Microbial Technol, Qingdao 266237, Peoples R China.

[Li, Dingjun] Hunan Univ Technol & Business, Changsha 410205, Peoples R China.

通讯机构：

[Dingjun Li; Wu Chen] C

College of Plant Protection, Hunan Agricultural University, Changsha, 410128 China<&wdkj&>College of Plant Protection, Hunan Agricultural University, Changsha, 410128 China<&wdkj&>Hunan University of Technology and Business, Changsha, 410205 China

语种：

英文

期刊：

MICROBIAL BIOTECHNOLOGY

ISSN：

1751-7915

年：

2022

卷：

期：

页码：

577-589

DOI：

10.1111/1751-7915.13825

基金类别：

National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31772216, 32000047]; National Natural Science Foundation of Hunan ProvinceNatural Science Foundation of Hunan Province [2019JJ40169, 2019JJ40119, 2019JJ40153]; Special Project for Construction of Innovative Province in Hunan [2019NK2192, 2020NK2006]; Key Research and Development Project in Changsha [kq2004031]

机构署名：

本校为第一机构

院系归属：

农学院

植物保护学院

摘要：

Edeines, a group of cationic antimicrobial peptides produced by the soil bacterium Brevibacillus, have broad biological effects, such as antimicrobial, anticancer and immunosuppressive activities. However, the yield of edeines in wild-type (WT) Brevibacillus is extremely low, and chemical synthesis of edeines is a time-consuming process. Genetic engineering has proven to be an effective approach to produce antibiotics with high yield. In this study, the edeine biosynthetic gene cluster (ede BGC), which is involved in edeine production, was iden...

反馈

产权有误：本人成果被他人认领

数据有误：数据基本信息有误

归属有误：成果的院系归属、机构署名归属有误

其他原因：

验证码：

看不清楚，换一个

确定

取消

成果认领

标题：

用户	作者	通讯作者	--
	请选择	请选择	--

确定

取消

Enhancement of edeine production in Brevibacillus brevis X23 via in situ promoter engineering

反馈

成果认领

提示

该栏目需要登录且有访问权限才可以访问