Kalpani River, Pakistan is an important stream that collects more than two third of the untreated domestic, commercial, industrial, and sewerage water, agricultural overflow, and other unwanted effluents of the surrounding area. These effluents have degraded the overall quality of this river water. The current study aims to examine the concentration of selected heavy metal (HM) contamination in Kalpani River sediments. The HMs studied were Pb, Cd, Zn, Ni, Fe, and Cu. Sediment samples were taken from nine selected locations (labeled as P1, P2, P...