期刊论文

Study on the anti-oxidation ability of two kinds of embedded chlorogenic acid products in vivo and in vitro

中文

扬州大学学报(农业与生命科学版)

1671-4652

2022

43

01

42-48

10.16872/j.cnki.1671-4652.2022.01.006

湖南省自然科学基金资助项目（2019JJ40134）； 湖南省教育厅科研项目（18A098）； 湖南省研究生科研创新项目（CX2018B404）；

本校为第一机构

绿原酸（chlorogenic acid, CGA）具有良好的生物活性，具有抗氧化、抗炎、降低血脂、预防糖尿病和高血压等特性，但其还原性强，难以长期保存，生物利用度较低。为提高绿原酸利用度，延长其生物活性，前期制备2种绿原酸包埋物，分别为单独用多孔淀粉包埋绿原酸产品CGAP （绿原酸+多孔淀粉组）以及同时用多孔淀粉和卵磷脂共包埋绿原酸产品CGAPP （绿原酸+多孔淀粉+卵磷脂组）,研究这2种绿原酸包埋物体内外抗氧化活性，并在体外测定包埋绿原酸随时间变化的稳定性。结果表明：这2种包埋工艺均能显著提高受到急性氧化损伤小鼠肝脏中超氧化物歧化酶和过氧化物酶活性，降低谷丙转氨酶活性和丙二醛含量...

Chlorogenic acid(CGA)has good biological activity,and is an important and biologically active dietary polyphenol.This polyphenol has many health-promoting properties,most of which are related to the treatment of metabolic syndrome,including antioxidant,anti-inflammatory,anti-lipid,anti-diabetic,and antihypertensive activities.Therefore,it has become an excellent candidate in the field of food additives and disease control.Because of its strong reducibility,it is difficult to store for a long time,and its bioavailability is relatively low.To improve the availability of chlorogenic acid and exte...