期刊论文

Differences in the effects of dietary lipids on the physiology and biochemistry of mice

中文

中国实验动物学报

1005-4847

2021

29

04

490-498

10.3969/j.issn.1005-4847.2021.04.010

湖南创新型省份建设专项经费资助（2020NK2032）~~；

本校为第一机构

目的探究不同饲料模型下不同油脂对小鼠生理生化指标的差异,为动物模型饲料油脂的选择、评价以及人类健康用油提供实验依据。方法以120只C57BL/6J雄性小鼠为研究对象,根据油脂供能设置两个水平,20%(低油脂供能水平)、30%(高油脂供能水平,推荐日常膳食脂肪供能比例不宜超过30%),每个油脂供能水平下分别选用猪油(LA)、菜籽油(RA)、橄榄油(OL)和猪油与菜籽油的调和油(质量比1 ∶ 1)(BO)。饲养16周后分析其对小鼠生长性能、脂肪沉积、血清生化指标以及血糖的影响。结果在低油脂供能水平下OL组小鼠的末体重极显著降低,肾周脂肪、附睾脂肪的积累极显著减少(P < 0.01),并且其Lee's指数也最低。在高油脂...

Objective To compare the effects of dietary oil content on the physiology and biochemistry of mice to provide a basis for the selection of appropriate oils for inclusion in animal feeds and for human health. Methods Two levels of dietary energy supply from oils were tested in male C57BL/6J mice: a 20% (low-oil energy supply) and 30% (high-oil energy supply), based on the recommendation that dietary energy supply in lipid form should not exceed 30%. Furthermore, each energy supply level was provided as lard (LA), rapeseed oil (RA), olive oil (OL...