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FZD7, Regulated by Non-CpG Methylation, Plays an Important Role in Immature Porcine Sertoli Cell Proliferation

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成果类型:
期刊论文
作者:
Yang, Anqi;Yan, Saina;Yin, Yanfei;Chen, Chujie;Tang, Xiangwei;...
通讯作者:
Maoliang Ran<&wdkj&>Bin Chen
作者机构:
[Yan, Saina; Chen, Chujie; Tang, Xiangwei; Yin, Yanfei; Ran, Maoliang; Yang, Anqi; Chen, Bin] Hunan Agr Univ, Coll Anim Sci & Technol, Hunan Prov Key Lab Genet Improvement Domest Anim, Changsha 410128, Peoples R China.
通讯机构:
[Maoliang Ran; Bin Chen] C
College of Animal Science and Technology, Hunan Provincial Key Laboratory for Genetic Improvement of Domestic Animal, Hunan Agricultural University, Changsha 410128, China<&wdkj&>Authors to whom correspondence should be addressed.
语种:
英文
关键词:
FZD7;non-CpG methylation;Sertoli cells;testes;proliferation;apoptosis
期刊:
International Journal of Molecular Sciences
ISSN:
1422-0067
年:
2023
卷:
24
期:
7
页码:
6179-
基金类别:
This work was financially supported by key R&D projects in Hunan Province (2020NK2024), an earmarked fund for the Hunan Provincial Agriculture Research System, and the Hunan Provincial Natural Science Foundation of China (2020JJ4348). The funders had no role in the study design, data collection and analysis, decision to publish, or preparation of the manuscript.
机构署名:
本校为第一机构
院系归属:
动物科学技术学院
摘要:
The regulatory role of non-CpG methylation in mammals has been important in whole-genome bisulfite sequencing. It has also been suggested that non-CpG methylation regulates gene expression to affect the development and health of mammals. However, the dynamic regulatory mechanisms of genome-wide, non-CpG methylation during testicular development still require intensive study. In this study, we analyzed the dataset from the whole-genome bisulfite sequencing (WGBS) and the RNA-seq of precocious porcine testicular tissues across two developmental s...

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