Lysine Restriction Affects Feed Intake and Amino Acid Metabolism via Gut Microbiome in Piglets

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成果类型：

期刊论文

作者：

Yin, Jie;Han, Hui;Li, Yuying;Liu, Zhaojin;Zhao, Yurong;...

通讯作者：

Li, Tiejun;Yin, Yulong

作者机构：

[Liu, Gang; Li, Chunyong; Wu, Xin; Li, Tiejun; Yin, Yulong; Han, Hui; Yin, Jie; Li, Yuying; Ren, Wenkai; Wu, Fei] Chinese Acad Sci, Key Lab Agroecol Proc Subtrop Reg, Sci Observing & Expt Stn Anim Nutr & Feed Sci Sou, Inst Subtrop Agr,Minist Agr,Hunan Prov Engn Res C, Changsha, Hunan, Peoples R China.

[Han, Hui; Yin, Jie; Li, Yuying; Ren, Wenkai; Wu, Fei] Univ Chinese Acad Sci, Beijing, Peoples R China.

[Zheng, Jie; Huang, Xingguo; Liu, Zhaojin; Fang, Rejun; Zhao, Yurong] Hunan Agr Univ, Dept Anim Sci, Changsha, Hunan, Peoples R China.

[Liu, Gang; Wu, Xin; Huang, Xingguo; Li, Tiejun; Yin, Yulong; Fang, Rejun; Zhao, Yurong] Hunan Coinnovat Ctr Anim Prod Safety, Changsha, Hunan, Peoples R China.

[Sun, Liping; Wang, Kai] Chinese Acad Agr Sci, Inst Apicultural Res, Beijing, Peoples R China.

通讯机构：

[Li, TJ; Yin, YL] C

Chinese Acad Sci, Inst Subtrop Agr, Key Lab Agroecol Proc Subtrop Reg, Changsha, Hunan, Peoples R China.

语种：

英文

关键词：

Feed intake;Lysine restriction;Microbiome;Piglet

期刊：

Cellular Physiology and Biochemistry

ISSN：

1015-8987

年：

2018

卷：

期：

页码：

1749-1761

DOI：

10.1159/000485782

基金类别：

National Basic Research Program of China (973)National Basic Research Program of China [2013CB127301]; Hunan Key Research Program [2017NK2320]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31472106]; China Agriculture Research System [CARS-35]

机构署名：

本校为其他机构

院系归属：

动物科学技术学院

摘要：

Background/Aims: Our previous reports suggested that dietary supplementation with lysine influenced intestinal absorption and metabolism of amino acids. In this study, we further investigated the effect of lysine restriction (30%) on feed intake and we also tested the hypothesis that gut microbiome contributed to the potential mechanism of lysine restriction-mediated feeding behavior. Here, we profiled gut microbial communities by sequencing 16S ribosomal ribonucleic acid (rRNA) genes from gut samples as well as growth performance, serum hormones, and intestinal lysine transport in a piglet mo...

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Lysine Restriction Affects Feed Intake and Amino Acid Metabolism via Gut Microbiome in Piglets

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