期刊论文

Effects of Exogenous MLT and RFRP-3 on Growth and Reproductive Performance of Male Mice at the Puberty

中文

中国畜牧兽医

1671-7236

2022

49

07

2622-2630

10.16431/j.cnki.1671-7236.2022.07.020

32072730:国家自然科学基金 2018KZDXM039:广东省教育厅基础研究重大项目 2020KJ137:广东省现代农业水禽产业技术体系创新团队

本校为第一机构

【目的】探究外源性RF-酰胺相关肽3（RF-amide related peptide 3,RFRP-3）和褪黑素（melatonin, MLT）对雄性昆明小鼠初情期生长、繁殖性能的影响及两者之间的关系。【方法】以初情期雄性昆明小鼠为研究对象，单独给予雄鼠生理盐水、外源性RFRP-3或MLT以及混合给予RFRP-3、MLT,检测其对雄鼠平均增重、平均采食量、料重比、睾丸发育情况，血清生长激素（growth hormone, GH）、黄体生成素（luteinizing hormone, LH）水平，以及生长、生殖相关基因表达的影响。【结果】外源性RFRP-3能抑制雄鼠GH基因表达，并抑制体重增长，提高料重比；而外源性MLT促进雄鼠GH基因表达，使体重增长较快，料重比降...

【Objective】This experiment was conducted to investigate the effects of exogenous RF-amides related peptide 3(RFRP-3)and melatonin(MLT)on the growth and reproductive performance of male Kunming mice at the beginning of estrus,and the relationship between them.【Method】Male Kunming mice at the beginning of estrus were given normal saline,exogenous RFRP-3,MLT,and a mixture of RFRP-3 and MLT,respectively.The effects on average weight gain,average feed intake,feed gain ratio(F/G),testicular development,the secretion levels of serum growth hormone...