Lotus seed skin proanthocyanidin extract exhibits potent antioxidant property via activation of the Nrf2-ARE pathway

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期刊论文

作者：

Li, Tao;Li, Qili;Wu, Weiguo;Li, Yong;Hou, De-xing;...

通讯作者：

Lu, Xiangyang;Deng, Fangming;Qin, Si

作者机构：

[Lu, Xiangyang; Qin, Si; Li, Yong; Li, Tao; Deng, Fangming; Wu, Weiguo; Hou, De-xing; Lu, XY; Qin, S] Hunan Agr Univ, Coll Food Sci & Technol, Key Lab Food Sci & Biotechnol Hunan Prov, Core Res Program 1515, Changsha 410128, Hunan, Peoples R China.

[Li, Qili; Shan, Yang] Hunan Acad Agr Sci, Hunan Agr Prod Proc Inst, Changsha 410125, Hunan, Peoples R China.

[Qin, Si; Hou, De-xing] Kagoshima Univ, United Grad Sch Agr Sci, Fac Agr, Kagoshima 8900065, Japan.

[Xu, Hua; Qin, Si] Univ Arizona, Dept Pediat, Steele Childrens Res Ctr, Tucson, AZ 85724 USA.

[Zheng, Baodong; Zeng, Shaoxiao] Fujian Agr & Forestry Univ, Dept Food Safety, Coll Food Sci, Fuzhou 350002, Fujian, Peoples R China.

通讯机构：

[Lu, XY; Deng, FM; Qin, S] H

[Qin, Si] K

[Qin, Si] U

Hunan Agr Univ, Coll Food Sci & Technol, Key Lab Food Sci & Biotechnol Hunan Prov, Core Res Program 1515, Changsha 410128, Hunan, Peoples R China.

Kagoshima Univ, United Grad Sch Agr Sci, Fac Agr, Kagoshima 8900065, Japan.

语种：

英文

关键词：

lotus seed skin extract;proanthocyanidin;Nrf2-ARE pathway;antioxidant activity

期刊：

生物化学与生物物理学报

ISSN：

1672-9145

年：

2018

卷：

期：

页码：

31-40

DOI：

10.1093/abbs/gmy148

基金类别：

This work was partially supported by the grants from the National Natural Science Foundation of China (No. 31101268) and Core Research Program 1515 of Hunan Agricultural University.

机构署名：

本校为第一且通讯机构

院系归属：

食品科学技术学院

摘要：

Lotus seed is well known as traditional food and medicine, but its skin is usually discarded. Recent studies have shown that lotus seed skin contains a high concentration of proanthocyanidins that have multi-functions, such as antioxidation, anti-inflammation, and anti-cancer effects. In the present study, we aimed to isolate and purify the proanthocyanidins from lotus seed skin by acetone extraction and rotary evaporation, identify their chemical structures by HPLC-MS-MS and NMR, and further investigate the antioxidant properties of the extract purified by macroporous resin (PMR) from lotus s...

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Lotus seed skin proanthocyanidin extract exhibits potent antioxidant property via activation of the Nrf2-ARE pathway

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