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Metabolomic and Transcriptomic Analysis of Effects of Three MUFA‐Rich Oils on Hepatic Glucose and Lipid Metabolism in Mice

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成果类型:
期刊论文
作者:
Zhou, Yingfang;Zhang, Linyu;Guo, Fangrui;Liu, Xiangyan;Li, Xin;...
通讯作者:
Wen, Lixin;Wang, J
作者机构:
[Zhou, Yingfang; Wang, Ji; Zhang, Linyu; Wen, Lixin; Guo, Fangrui; Liu, Xiangyan; Li, Xiaowen; Wang, J; Li, Xin; Shi, Xingyong] Hunan Agr Univ, Coll Vet Med, Hunan Engn Res Ctr Livestock & Poultry Hlth Care, Changsha 410128, Peoples R China.
[Li, Xin] Changsha Lvye Biotechnol Co Ltd, Changsha 410100, Peoples R China.
[Han, Zongding] Hunan Agr Univ, Orient Sci & Technol Coll, Changsha 410128, Peoples R China.
[Wang, Ji] Hunan Agr Univ, Coll Anim Sci & Technol, Anim Nutr Genome & Germplasm Innovat Res Ctr, Changsha 410128, Peoples R China.
通讯机构:
[Wen, LX; Wang, J ] H
Hunan Agr Univ, Coll Vet Med, Hunan Engn Res Ctr Livestock & Poultry Hlth Care, Changsha 410128, Peoples R China.
语种:
英文
关键词:
Lard;Lipid metabolism;Monounsaturated fatty acids;Olive oil;Omic analysis;Rapeseed oil
期刊:
MOLECULAR NUTRITION & FOOD RESEARCH
ISSN:
1613-4125
年:
2023
卷:
67
期:
23
页码:
2300398-
基金类别:
The authors would like to thank the Special Funds for the Construction of Innovative Provinces in Hunan Province (Grant No. 2020NK2032). They would also like to thank Editage () for the English language editing. [2020NK2032]; Special Funds for the Construction of Innovative Provinces in Hunan Province
机构署名:
本校为第一且通讯机构
院系归属:
动物科学技术学院
动物医学院
东方科技学院
摘要:
ScopeOlive oil, rapeseed oil, and lard are dietary fats rich in monounsaturated fatty acids, but the effects of dietary oils enriched in monounsaturated fatty acids on hepatic lipid deposition have seldom been compared.Methods and resultsNinety 8-week-old C57BL/6J male mice are randomly divided into six groups and fed diets containing lard, rapeseed oil, or olive oil with a 10% or 45% fat energy supply for 16 weeks. Under high-fat conditions, serum total cholesterol levels in the lard and olive oil groups are significantly higher than those in the rapeseed oil group. Hepatic lipid content in t...

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