Blue biotechnology is also called marine biotechnology, refers to the intergration of micro-and macrobiotechnologies,including gene engineering, cell engineering, and biochemical engineering applied in ma- rine life and ecological engineering applied in marine ecological environment, etc. It is the fusion of multiple dis- ciplines, such as molecular biology, microbiology, materials chemistry, engineering, medicine, ecology and so on. This paper reviewed the development advantages and the research field of blue biotechnology,and summarized the r...