Objective: To investigate the impact of childhood traumatic experience on depression, and the moderating effects of self-esteem. Methods: Correlation and Hierarchical Regression Analysis were used to analysze the surveyed data collected from 1219 middle school students and college students. Results: All the standard regression coefficients of emotional abuse, emotional neglect, physical neglect, sexual abuse to depression were positive and significant; The standard regression coefficients of self-esteem to depression were negative and signif...