期刊论文

英文

Pesticide Biochemistry and Physiology

0048-3575

2023

196

105589

10.1016/j.pestbp.2023.105589

Thanks to professor Michael H. Court of the UGTs nomenclature committee for naming of UGT genes. This work was sponsored by the National Natural Science Foundation of China ( 31801764 ). Thanks to professor Michael H. Court of the UGTs nomenclature committee for naming of UGT genes. This work was sponsored by the National Natural Science Foundation of China (31801764).

本校为第一机构

UDP-glycosyltransferase (UGT) is the major detoxification enzymes of phase II involved in xenobiotics metabolism, which potentially mediates the formation of insect resistance. Previous transcriptome sequencing studies have found that several UGT genes were upregulated in indoxacarb resistant strains of Spodoptera litura, but whether these UGT genes were involved in indoxacarb resistance and their functions in resistance were unclear. In this study, the UGTs inhibitor, 5-nitrouracil, enhanced the toxicity of indoxacarb against S. litura, prelim...