Emergence of the resistance-nodulation-division efflux pump tmexCD3-toprJ3 gene confers resistance to tigecycline in Pseudomonas juntendi and Proteus terrae isolated from a pig farm in China

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成果类型：

期刊论文

作者：

Yang, Jie;Zeng, Ziyue;Hu, Jufang;Liu, Zhihong;Gu, Jinrong;...

通讯作者：

Zhiliang Sun<&wdkj&>Jiyun Li

作者机构：

[Hu, Jufang; Chen, Xiaojun; Zeng, Ziyue; Gu, Jinrong; Yang, Jie; Liu, Zhihong; Sun, Zhiliang; Li, Jiyun] Hunan Agr Univ, Coll Vet Med, Changsha, Hunan, Peoples R China.

[Hu, Jufang; Chen, Xiaojun; Zeng, Ziyue; Gu, Jinrong; Yang, Jie; Liu, Zhihong; Sun, Zhiliang; Li, Jiyun] Hunan Agr Univ, Hunan Engn Technol Res Ctr Vet Drugs, Changsha, Hunan, Peoples R China.

通讯机构：

[Zhiliang Sun; Jiyun Li] C

College of Veterinary Medicine, Hunan Agricultural University, Changsha, Hunan, China<&wdkj&>Hunan Engineering Technology Research Center of Veterinary Drugs, Hunan Agricultural University, Changsha, Hunan, China

语种：

英文

关键词：

Proteus terrae;Pseudomonas juntendi;resistance-nodulation-division;tigecycline;tmexCD3-toprJ3

期刊：

Veterinary Medicine and Science

ISSN：

2053-1095

年：

2022

卷：

期：

页码：

2460-2465

DOI：

10.1002/vms3.950

基金类别：

China Postdoctoral Science Foundation#&#&#2020M682569

机构署名：

本校为第一机构

院系归属：

动物医学院

摘要：

AbstractBackgroundTigecycline is regarded as a last‐resort antimicrobial agent against multidrug resistance (MDR). However, resistance‐nodulation‐division efflux pump resistance genes, such as tmexCD3‐toprJ3, that confer resistance to tigecycline have emerged.ObjectivesThis study aimed to characterise the tmexCD3‐toprJ3 gene cluster in Pseudomonas juntendi and Proteus terrae isolated from a pig farm.MethodsSamples were obtained from a Chinese piggery and included 92 pig faecal samples, 56 wastewater samples, 23 drinking water samples, 28 s...

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Emergence of the resistance-nodulation-division efflux pump tmexCD3-toprJ3 gene confers resistance to tigecycline in Pseudomonas juntendi and Proteus terrae isolated from a pig farm in China

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