Regulation of N-Carbamyl Glutamate,Proline and Putrescine on Sodium Dependent Neutral Amino Acid Transporter-2 Expression and Nutrition Sensing Signaling in Jejunum and Ileum of Piglets
本研究旨在探讨Na~+依赖性中性氨基酸转运载体2(SNAT2)介导多胺及其前体物质对仔猪肠黏膜营养感应信号的调控作用。试验选取32头哺乳仔猪,随机分为4组,每组8头猪,自出生当日开始,每日2次分别灌服生理盐水(对照组) 、腐胺(5 mg / kg BW) 、脯氨酸(25 mg / kg BW)和N-氨甲酰谷氨酸(NCG,8 mg / kg BW) 。14日龄断奶,断奶第3天采血后屠宰,采集空肠和回肠样品。结果表明:与对照组相比,灌服腐胺、脯氨酸和NCG显著提高仔猪平均日增重(P
摘要(英文)：
The purpose of this study was to investigate regulation of the sodium dependent neutral amino acid transporter-2 (SNAT2) on the nutrition sensing signaling of intestinal mucosa of piglets via polyamines.Thirtytwo neonatal piglets (Duroc×Landrace×Large Yorkshire) from 4 litters (8 piglets per litter) were assigned to 4 groups,which received oral administration of equal volumes of saline (control group),putrescine(5 mg / kg BW),proline (25 mg / kg BW) and N-carbamylglutamate (NCG,8 mg / kg BW) twice daily from days 1 to 14.At day 3 post-weaning...
