A highly sensitive tetracycline sensor based on a combination of magnetic molecularly imprinted polymer nanoparticles and surface plasmon resonance detection
National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31671931, 31601551]; "1515" talent cultivation plan of Hunan Agricultural University
机构署名：
本校为第一且通讯机构
院系归属：
食品科学技术学院
摘要：
A method is reported for in-situ detection of the antibiotic tetracycline (TC). It is based on a combination of extraction of TC by magnetic molecularly imprinted polymers nanoparticles (MMIPs NPs) and detection by surface plasmon resonance (SPR). The TC-captured MMIPs NPs were flowed over the surface of the SPR chip that was modified with mercaptoethylamine. The SPR signal undergoes a strong increase through the use of MMIPs NPs. It increases linearly in the 5.0-100 pg center dot mL(-1) TC concentration range, and the detection limit is as low as 1.0 pg center dot mL(-1) (at S/N = 3). This me...
