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Screening of probiotic Lactobacilli with potential anti-allergic activity based on hyaluronidase inhibition and degranulation of RBL-2H3 cells in vitro

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成果类型:
期刊论文
作者:
Lei, Wenping;Liu, Chengguo;Pan, Lina;Peng, Can;Wang, Jiaqi;...
通讯作者:
Jiaqi Wang<&wdkj&>Hui Zhou
作者机构:
[Liu, Chengguo; Lei, Wenping; Zhou, Hui] Hunan Agr Univ, Coll Food Sci & Technol, 1 Nongda Rd, Changsha 410125, Hunan, Peoples R China.
[Peng, Can; Wang, Jiaqi; Pan, Lina] Ausnutria Dairy China Co Ltd, 168 Huangxing Middle Rd, Changsha 410125, Hunan, Peoples R China.
通讯机构:
[Jiaqi Wang] A
[Hui Zhou] C
Ausnutria Dairy (China) Co., Ltd., Changsha, Hunan, China<&wdkj&>College of Food Science and Technology, Hunan Agricultural University, Changsha, Hunan, China
语种:
英文
关键词:
Cell membranes;Cytology;Diagnosis;Diseases;Lactic acid;Allergic disease;Anti-allergic activities;Immunoblot analysis;Inflammatory disease;Inhibition assays;Lactic acid bacteria;Probiotic lactobacilli;Probiotic potentials;Probiotics
期刊:
LWT
ISSN:
0023-6438
年:
2021
卷:
140
页码:
110707
基金类别:
CRediT authorship contribution statement Wenping Lei: Conceptualization, Data curation, Writing - original draft, Resources. Chengguo Liu: Conceptualization, Methodology, Writing - review & editing, acquisition. Lina Pan: Software, Writing - review & editing, Supervision. Can Peng: Supervision, Writing - review & editing. Jiaqi Wang: Supervision, Methodology, Writing - review & editing. Hui Zhou: Conceptualization, Methodology, Visualization, Writing - review & editing, Investigation, Project administration, Funding
机构署名:
本校为第一机构
院系归属:
食品科学技术学院
摘要:
In the present study, the probiotic potential of lactic acid bacteria (LAB) isolated from different dairy sources were evaluated, and probiotics with anti-allergic activity were further screened based on the hyaluronidase inhibition assay and the degranulation of RBL-2H3 cells in vitro. As a result, Out of 20 strains, 15 LAB exhibited desirable probiotic properties and safety in vitro. Considering the suppressive activities on hyaluronidase and beta-hexosaminidase release in degranulation-induced RBL-2H3 cells, strains LZ077E, LZ183E, and LZ260E exhibited potential probiotic properties that co...

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