期刊论文

Fang, Jun(fangjun1973@hunau.edu.cn)

英文

ANALYST

0003-2654

2022

147

18

3958-3973

10.1039/d2an00679k

National Natural Science Foundation of China [31672457, 22004035]; China Postdoctoral Science Foundation [2020TQ0094, 2020M682565]; Hunan Provincial Science and Technology Department [2020NK2004, 2020ZL2004, 2021JJ40230]; Double first-class construction project of Hunan Agricultural University [SYL2002454451802003, CX20190497]; Science and Technology Innovation Program of Hunan Province [2020RC2054]; Opening Fund of Key Laboratory of Chemical Biology and Traditional Chinese Medicine Research (Hunan Normal University)

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With the rapid development of physiopathology and the surge in demand for comprehension of micro-scale physiological events, AIE-based bio-probes are found superior in presenting precise and practical results in enzyme imaging and analysis with a high signal-to-noise ratio and non-destructive operation. By delivering enzyme-responding 'light-up' fluorescence signals, the visual and real-time tracking of the distribution and activity of intracellular enzymes is accomplished with AIE-based bio-probes. In particular, by combining with modern nano-...