期刊论文

Liu, Gang

英文

中国科学:生命科学(英文版)

1674-7305

2021

64

11

1906-1916

10.1007/s11427-020-1835-4

supported by the National Natural Science Foundation of China （31772642, 31672457）； Hunan Provincial Science and Technology Department （2019TP2004, 2017NK2322, 2016WK2008, 2016TP2005）； Double first-class construction project of Hunan Agricultural University （SYL201802003）； China Postdoctoral Science Foundation （2018M632963, 2019T120705）；

本校为第一且通讯机构

Inflammatory bowel disease (IBD) is a chronic lifelong disease characterized by inflammation of the gastrointestinal tract. Although more and more treatment options serve IBD, there is still no cure. It is important to find an effective treatment for IBD. This study aims to investigate whether Lactobacillus plantarum (L. plantarum) could alleviate colitis induced by dextran sulfate sodium (DSS). Following the DSS challenge, L. plantarum on DSS-mediated inflammatory colon lesions in mice, and L. plantarum therapy heightened the relative abundance of the colon-resident Actinobacteria. Analysis o...