期刊论文

Li, Qingjie

英文

Hepatology Research

1386-6346

2011

41

8

776-783

10.1111/j.1872-034X.2011.00827.x

NIHUnited States Department of Health & Human ServicesNational Institutes of Health (NIH) - USA [CA80176]; NATIONAL CANCER INSTITUTEUnited States Department of Health & Human ServicesNational Institutes of Health (NIH) - USANIH National Cancer Institute (NCI) [P01CA090890, R01CA122959, P01CA090890, P01CA090890, P01CA090890, P01CA090890, P01CA090890, R01CA080176, P01CA090890, P01CA090890, P01CA090890, R01CA080176, P01CA090890, P01CA090890, P01CA090890, R01CA122959, P01CA090890, P01CA090890, P01CA090890, P01CA090890, P01CA090890, R01CA080176, P01CA090890, P01CA090890, P01CA090890, P01CA090890, R01CA122959, P01CA090890, R01CA122959, P01CA090890, P01CA090890, P01CA090890, P01CA090890, P01CA090890, P01CA090890, R01CA080176, R01CA122959, P01CA090890, P01CA090890, P01CA090890, P01CA090890, R01CA080176, P01CA090890, R01CA122959, P01CA090890, P01CA090890, P01CA090890, R01CA122959, P01CA090890, P01CA090890, P01CA090890, P01CA090890] Funding Source: NIH RePORTER

本校为其他机构

Aim: Activator protein 2 alpha (AP-2 alpha) belongs to the AP-2 family of transcription factors that are involved in the regulation of cell proliferation, differentiation, apoptosis and carcinogenesis and has been suggested to function as a tumor suppressor in many cancers. However, the physiological role of AP-2 alpha in hepatocytes is unknown. The present study is to characterize the expression and function of AP-2 alpha in the liver of conscience mouse. Methods: Exogenous AP-2 alpha was overexpressed in the mouse liver by in vivo gene delivery and changes in transcription factor expression ...