期刊论文

Li, Qingjie

英文

Hepatology Research

1386-6346

2011

41

8

776-783

10.1111/j.1872-034X.2011.00827.x

NIHUnited States Department of Health & Human ServicesNational Institutes of Health (NIH) - USA [CA80176]; NATIONAL CANCER INSTITUTEUnited States Department of Health & Human ServicesNational Institutes of Health (NIH) - USANIH National Cancer Institute (NCI) [P01CA090890, R01CA122959, P01CA090890, P01CA090890, P01CA090890, P01CA090890, P01CA090890, R01CA080176, P01CA090890, P01CA090890, P01CA090890, R01CA080176, P01CA090890, P01CA090890, P01CA090890, R01CA122959, P01CA090890, P01CA090890, P01CA090890, P01CA090890, P01CA090890, R01CA080176, P01CA090890, P01CA090890, P01CA090890, P01CA090890, R01CA122959, P01CA090890, R01CA122959, P01CA090890, P01CA090890, P01CA090890, P01CA090890, P01CA090890, P01CA090890, R01CA080176, R01CA122959, P01CA090890, P01CA090890, P01CA090890, P01CA090890, R01CA080176, P01CA090890, R01CA122959, P01CA090890, P01CA090890, P01CA090890, R01CA122959, P01CA090890, P01CA090890, P01CA090890, P01CA090890] Funding Source: NIH RePORTER

本校为其他机构

Aim:  Activator protein 2α (AP‐2α) belongs to the AP‐2 family of transcription factors that are involved in the regulation of cell proliferation, differentiation, apoptosis and carcinogenesis and has been suggested to function as a tumor suppressor in many cancers. However, the physiological role of AP‐2α in hepatocytes is unknown. The present study is to characterize the expression and function of AP‐2α in the liver of conscience mouse.Methods:  Exogenous AP‐2α was overexpressed in the mouse liver by in vivo gene delivery and chang...