期刊论文

Chen, Junhua

英文

Food Chemistry

0308-8146

2021

346

128975

10.1016/j.foodchem.2020.128975

This work was supported by the Local Innovative and Research Teams Project of Guangdong Pearl River Talents Program ( 2017BT01Z176 ), Provincial Excellent Doctoral Dissertation Cultivation Fund Project of Hunan Agricultural University ( YB2019001 ), Hunan Province Graduate Research and Innovation Project ( CX20200654 ), and GDAS' Project of Science and Technology Development ( 2020GDASYL-20200302007 ).

本校为其他机构

As bisphenol A (BPA) is harmful to human health, it is of great significance to develop a new method for BPA detection. Herein, we designed a BPA biosensor by integrating an amplifying DNA circuit with Mg2+-dependent DNAzyme into the sensing system. The BPA-aptamer binding activated a DNA circuit for signal amplification based on toehold-mediated strand displacement. A catalytic Mg2+-dependent DNAzyme was formed through synergistically DNA hybridization, which can cleave the dual-labeled substrate DNA into two segments. The separation of the fl...