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Obese Ningxiang pig-derived microbiota rewires carnitine metabolism to promote muscle fatty acid deposition in lean DLY pigs

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成果类型:
期刊论文
作者:
Yin, Jie;Li, Yunxia;Tian, Yu;Zhou, Feng;Ma, Jie;...
通讯作者:
Yulong Yin<&wdkj&>Xingguo Huang
作者机构:
[Yin, Jie; Li, Yunxia; Tian, Yu; Zhou, Feng; Ma, Jie; Xia, Siting; Yang, Tong; Liu, Gang; Huang, Xingguo] College of Animal Science and Technology, Hunan Agriculture University, Changsha 410128, China
[Ma, Libao] College of Animal Sciences and Technology, Huazhong Agricultural University, Wuhan 430070, China
Hunan Chuweixiang Agriculture and Animal Husbandry Co., Ltd., Ningxiang 410600, China
Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha 410125, China
[Zeng, Qinghua] College of Animal Science and Technology, Hunan Agriculture University, Changsha 410128, China<&wdkj&>Hunan Chuweixiang Agriculture and Animal Husbandry Co., Ltd., Ningxiang 410600, China
通讯机构:
[Yulong Yin; Xingguo Huang] C
College of Animal Science and Technology, Hunan Agriculture University, Changsha 410128, China<&wdkj&>College of Animal Science and Technology, Hunan Agriculture University, Changsha 410128, China<&wdkj&>Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha 410125, China
语种:
英文
期刊:
创新(英文)
ISSN:
2666-6758
年:
2023
卷:
4
期:
5
页码:
100486
机构署名:
本校为第一且通讯机构
院系归属:
动物科学技术学院
摘要:
The gut microbiota consistently shows strong correlations with lipid metabolism in humans and animals, and whether the gut microbiota contributes to muscle fatty acid (FA) deposition and meat traits in farm animals has not been fully resolved. In this study, we aimed to unveil the microbial mechanisms underlying muscle FA deposition in pigs. First, we systematically revealed the correlation between the gut microbiome and muscle FA levels in 43 obese Ningxiang pigs and 50 lean Duroc Landrace Yorkshire (DLY) pigs. Mutual fecal microbial transplantation showed that the obese Ningxiang pig-derived...

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