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Fuzhuan brick tea polysaccharides serve as a promising candidate for remodeling the gut microbiota from colitis subjects in vitro: Fermentation characteristic and anti-inflammatory activity

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成果类型:
期刊论文
作者:
Chen, Guijie;Wang, Mingjia;Zeng, Ziqi;Xie, Minhao;Xu, Weiqi;...
通讯作者:
Zeng, Xiaoxiong(zengxx@njau.edu.cn)
作者机构:
[Chen, Guijie; Xu, Weiqi; Zeng, Ziqi; Peng, Yujia; Wang, Mingjia; Zeng, Xiaoxiong; Sun, Yi; Zhou, Wangting] Nanjing Agr Univ, Coll Food Sci & Technol, Nanjing 210095, Jiangsu, Peoples R China.
[Xie, Minhao] Nanjing Univ Finance & Econ, Coll Food Sci & Engn, Collaborat Innovat Ctr Modern Grain Circulat & Saf, Nanjing 210023, Peoples R China.
[Liu, Zhonghua] Hunan Agr Univ, Key Lab Minist Educ Tea Sci, Changsha 410128, Peoples R China.
[Liu, Zhonghua] Natl Res Ctr Engn Technol Utilizat Bot Funct Ingre, Changsha 410128, Peoples R China.
通讯机构:
[Zeng, X.] K
Key Laboratory of Ministry of Education for Tea Science, Hunan Agricultural University, Changsha, China
语种:
英文
关键词:
Colitis;Fuzhuan brick tea;Gut microbiota;Polysaccharides;Prebiotics;Short-chain fatty acids
期刊:
Food Chemistry
ISSN:
0308-8146
年:
2022
卷:
391
页码:
133203
基金类别:
The study was supported by the National Natural Science Foundation of China (No. 31972025), Fundamental Research Funds for the Central Universities (KJQN202154), National Key Research and Development Program of China (2018YFC1604404) and a project funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions.
机构署名:
本校为其他机构
院系归属:
园艺园林学院
摘要:
The purified fraction 3 of polysaccharides from Fuzhuan brick tea (FBTPS-3) could attenuate the colitis and modulate the gut microbiota. However, the relationship between anti-inflammatory effect of FBTPS-3 and the gut microbiota is still unknown. Thus, the anaerobic fermentation in vitro was used to investigate the potential mechanism. FBTPS-3 could be utilized and degraded by gut microbiota from inflammatory bowel disease (IBD) subjects. Furthermore, FBTPS-3 could modulate the composition and structure of IBD gut microbiota toward to that of ...

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