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Development of a Rapid Method for the Confirmatory Analysis of Flunixin Residue in Animal Tissues Using Liquid Chromatography–Tandem Mass Spectrometry

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成果类型:
期刊论文
作者:
Liu, Zhao-Ying;Yang, Kun;Chen, Fu-Hua;Long, Xue-Ming;Deng, Yun-Bo;...
通讯作者:
Sun, Zhi-Liang
作者机构:
[Sun, Zhi-Liang; Yang, Kun; Liu, Zhao-Ying] Hunan Agr Univ, Coll Vet Med, Hunan Engn Res Ctr Vet Drug, Changsha 410128, Hunan, Peoples R China.
[Kuang, Guang-Wei; Chen, Fu-Hua; Deng, Yun-Bo; Long, Xue-Ming] Hunan Prov Inst Anim Drug & Feed Supervis, Changsha 410006, Hunan, Peoples R China.
通讯机构:
[Sun, Zhi-Liang] H
Hunan Agr Univ, Coll Vet Med, Hunan Engn Res Ctr Vet Drug, Changsha 410128, Hunan, Peoples R China.
语种:
英文
关键词:
Animal tissues;Flunixin;Liquid chromatography–tandem mass spectrometry;Residue;Validation method
期刊:
Food Analytical Methods
ISSN:
1936-9751
年:
2015
卷:
8
期:
2
页码:
352-362
基金类别:
Ministry of Agriculture of the People's Republic of ChinaMinistry of Agriculture, China
机构署名:
本校为第一且通讯机构
院系归属:
动物医学院
摘要:
Flunixin is approved for use in veterinary medicine as a nonsteroidal anti-inflammatory agent. There is a need for the control of residues and development of methods to monitor its compliance with legislation. However, few methods have been reported for the analysis of flunixin in the animal liver, kidney, and fat. Therefore, the aim of this work was to develop a relatively rapid sample preparation and sensitive using liquid chromatography–tandem mass (LC-MS/MS) confirmatory method to detect flunixin residues in the liver, kidney, muscle, and fat of swine and chicken. After acid hydrolys...

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