期刊论文

中文

生命科学研究

1007-7847

2013

17

4

348-353

10.16605/j.cnki.1007-7847.2013.04.010

国家自然科学青年基金资助项目(31101741)；

本校为第一机构

长链脂肪酸在哺乳动物体内具有广泛的生理功能,特别是在生物膜的形成和动态特性维持中发挥着不可或缺的作用,同时,作为能量产生的重要原料,长链脂肪酸在保持心脏和骨骼肌正常功能方面也具有极其重要的作用.脂肪酸转运蛋白家族(fatty acid transport proteins, FATPs)是一组膜蛋白,在心脏、肝脏、肌肉和小肠等脂肪酸代谢活跃的组织器官中均有表达.已有研究表明,FATPs在长链脂肪酸的摄取和代谢调节中发挥着重要作用,现对FATPs的组织分布、结构特点、功能、作用机制及其与人类疾病的关系等方面进行综述.

Long chain fatty acids have a wide range of physiological functions in mammals, especially playing an indispensable role in biofilm formation and maintenance of dynamic characteristics. Meanwhile, as important raw material for producing energy, long chain fatty acids have an extremely important role in maintaining normal functions of heart and skeletal muscle. Fatty acid transport proteins （FATPs） family is a group of membrane proteins and expressed in many tissues and organs with active fatty acid metabolism, e. g. heart, liver, muscle, and ...