Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31172377, 31272630, 31572591]; Key Projects of Hunan Province Education Office [14A069]
机构署名:
本校为第一且通讯机构
院系归属:
动物医学院
摘要:
Peroxisome proliferator-activated receptor (PPAR) γ has been reported to be implicated in placentation in mice. Previous studies have demonstrated that PPARγ is also expressed in porcine placenta, primarily localized in vascular endothelial cells (VECs). The present study aimed to investigate the roles of PPARγ during porcine placental angiogenesis and examine the molecular mechanisms involved in its actions. VECs were incubated with the PPARγ agonist rosiglitazone and the antagonist T0070907, and their angiogenic potential was evaluated us...