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Effects of Ursolic Acid on Intestinal Health and Gut Bacteria Antibiotic Resistance in Mice

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成果类型:
期刊论文
作者:
Peng, Fang;Zhang, Haihan;He, Xi;Song, Zehe
通讯作者:
He, X.;Song, Z.
作者机构:
[Song, Zehe; He, Xi; Peng, Fang; Zhang, Haihan] Hunan Agr Univ, Coll Anim Sci & Technol, Changsha, Peoples R China.
[Song, Zehe; He, Xi; Peng, Fang; Zhang, Haihan] Minist Educ Engn Res Ctr Feed Safety & Efficient, Changsha, Peoples R China.
通讯机构:
[He, X.; Song, Z.] C
College of Animal Science and Technology, China
语种:
英文
关键词:
Ursolic acid;anti-inflammation;substitute of antibiotics;ARG;intestine.
期刊:
Frontiers in Physiology
ISSN:
1664-042X
年:
2021
卷:
12
页码:
650190
基金类别:
This work was supported by the National Key R&D Program of Intergovernmental Key Projects of China (Grant No. 2018YFE0101700) and Support Project for Scientific and Technical Talents in Hunan Province (2020TJ-Q02).
机构署名:
本校为第一机构
院系归属:
动物科学技术学院
摘要:
Ursolic acid (UA), a natural pentacyclic triterpenoid, has been widely reported to exert anti-oxidant and anti-inflammatory properties. However, the effects of UA on the intestinal homeostasis and gut microbiota were rarely explored. The aim of the present study was to investigate the effects of UA on intestinal health and gut microflora antibiotic-resistance in antibiotic-exposed mice. Kunming mice (n = 80) were randomly allocated into three groups and fed with one of the following diets, respectively: Cont group (n = 20), the basal diet; UA g...

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