Epidermal stem cells(ESCs) are mainly located in basal layer and the bulge of the outer root sheath,characterized by non-differentiation,multiplying and self-renewing abilities.Isolation and culture epidermal stem cells in vitro,cultivating skin organ sample and using tissue engineering method to study the proliferation and differentiation,Though adding to our understanding of ESCs biology characteristics,this paper provides an overview of molecular mechanism on regulatingthe ...