Integrating large-scale meta-analysis of genome-wide association studies improve the genomic prediction accuracy for combined pig populations

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作者信息关键词期刊信息基础信息归属信息摘要

成果类型：

期刊论文

作者：

Cai, Xiaodian;Zhang, Wenjing;Gao, Ning;Wei, Chen;Wu, Xibo;...

通讯作者：

Zhang, Z

作者机构：

[Wei, Chen; Gao, Yahui; Li, Jiaqi; Zhang, Zhe; Cai, Xiaodian; Zhang, Wenjing] South China Agr Univ, Coll Anim Sci, Natl Engn Res Ctr Breeding Swine Ind, Guangdong Prov Key Lab Agroanim Genom & Mol Breed, Guangzhou, Peoples R China.

[Gao, Ning] Hunan Agr Univ, Coll Anim Sci & Technol, Changsha, Peoples R China.

[Wu, Xibo; Si, Jinglei] Guangxi State Farmd Yongxin Anim Husb Grp Co Ltd, Nanning, Peoples R China.

[Yin, Tong] Justus Liebig Univ, Inst Anim Breeding & Genet, Giessen, Germany.

[Zhang, Z] South China Agr Univ, Dept Anim Breeding & Genet, Guangzhou 510642, Peoples R China.

通讯机构：

[Zhang, Z ] S

South China Agr Univ, Dept Anim Breeding & Genet, Guangzhou 510642, Peoples R China.

语种：

英文

关键词：

combined population;genomic prediction;heritability enrichment;meta-analysis of genome-wide association studies

期刊：

JOURNAL OF ANIMAL BREEDING AND GENETICS

ISSN：

0931-2668

年：

2025

卷：

142

期：

页码：

223-236

DOI：

10.1111/jbg.12896

基金类别：

China Agriculture Research System [CARS- 35]; Selection and Breeding of New Local Pig Breeds and Promotion of Industrialization [2022-440000-43010101-9501]; Guangxi Science and Technology Program Project [GuikeJB23023003]

机构署名：

本校为其他机构

院系归属：

动物科学技术学院

摘要：

The strategy of combining reference populations has been widely recognized as an effective way to enhance the accuracy of genomic prediction (GP). This study investigated the efficiency of genomic prediction using prior information and combined reference population. In total, prior information considering trait-associated single nucleotide polymorphisms (SNPs) obtained from meta-analysis of genome-wide association studies (GWAS meta-analysis) was incorporated into three models to assess the performance of GP using combined reference populations...

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Integrating large-scale meta-analysis of genome-wide association studies improve the genomic prediction accuracy for combined pig populations

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