期刊论文

英文

Oxidative Medicine and Cellular Longevity

1942-0900

2021

2021

10.1155/2021/5546843

National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31802077, U19A2037, 31972582]; Training Program for Excellent Young Innovators of Changsha [kq2009020]; Natural Science Foundation of Guangxi ProvinceNational Natural Science Foundation of Guangxi Province [2020JJA130102, 2018JJB130239]; Special Funds for the Construction of Innovative Provinces in Hunan Project [2019NK2193, 2019RS3022]; Earmarked Fund for China Agriculture Research System [CARS-35]; "Strategic Priority Research Program" of the Chinese Academy of SciencesChinese Academy of Sciences [XDA24030204]; Fuyang Normal University Undertakes Fuyang Science and Technology Project [SXHZ202007]; Open Fund of Key Laboratory of Agro-ecological Processes in Subtropical Region, Chinese Academy of Sciences [ISA2020203, ISA2020204]

本校为其他机构

The current study was performed to investigate whether dietary beta-hydroxy-beta-methylbutyrate (HMB) could regulate liver injury in a lipopolysaccharide- (LPS-) challenged piglet model and to determine the mechanisms involved. Thirty piglets (21 +/- 2 days old, 5.86 +/- 0.18 kg body weight) were randomly divided into the control (a basal diet, saline injection), LPS (a basal diet), or LPS+HMB (a basal diet + 0.60% HMB-Ca) group. After 15 d of treatment with LPS and/or HMB, blood and liver samples were obtained. The results showed that in LPS-injected piglets, HMB supplementation ameliorated l...