DNA methylation pattern is associated with elevated expression of DGAT2 in hybrid tilapia

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成果类型：

期刊论文

作者：

Zhong, Huan;Zhou, Yi;Zhang, Hong;Xiao, Wei

通讯作者：

Yi Zhou

作者机构：

[Zhong, Huan] Hunan Agr Univ, Utilizat Distinct Aquat Resource, Hunan Res Ctr Engn Technol, Changsha, Peoples R China.

[Zhou, Yi] Hunan Normal Univ, State Key Lab Dev Biol Freshwater Fish, Engn Res Ctr Polyploid Fish Reprod & Breeding, State Educ Minist,Coll Life Sci, Changsha, Peoples R China.

[Zhang, Hong] Beibu Gulf Univ, Beibu Gulf Marine Biodivers Conservat, Guangxi Key Lab, Qinzhou, Peoples R China.

[Xiao, Wei] Chinese Acad Fishery Sci, Freshwater Fisheries Res Ctr, Minist Agr, Key Lab Freshwater Fisheries & Germplasm Resourc, Wuxi, Jiangsu, Peoples R China.

通讯机构：

[Yi Zhou] S

State Key Laboratory of Developmental Biology of Freshwater Fish, Engineering Research Center of Polyploid Fish Reproduction and Breeding of the State Education Ministry, College of Life Sciences, Hunan Normal University, Changsha, China

语种：

英文

关键词：

allele;DGAT2;epigenetic;hybridization;lipid metabolism;liver

期刊：

Aquaculture Nutrition

ISSN：

1353-5773

年：

2021

卷：

期：

页码：

1750-1760

DOI：

10.1111/anu.13312

基金类别：

Natural Science Foundation of Guangxi Zhuang Autonomous RegionNational Natural Science Foundation of Guangxi Province [2017GXNSFFA198001]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [31672627, 31760756]; Guangxi Key Laboratory of Beibu Gulf Marine Biodiversity Conservation, Beibu Gulf University [2020KB02]

机构署名：

本校为第一机构

摘要：

Lipid metabolism is a key biological process involving the synthesis and degradation of lipids in organisms. In the liver, triglyceride (TG) synthesis mediates the storage of fats for energy, which is catalysed by diacylglycerol acyltransferase-2 (DGAT2). Herein, we compared TG-related indexes in serum from Nile tilapia (Oreochromis niloticus), blue tilapia (O.aureus) and hybrid offspring (Nile tilapia ♀×blue tilapia ♂). The results showed that serum TG levels were significantly higher in the hybrid tilapia (6.95±1.48mmol/L) than that in bl...

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DNA methylation pattern is associated with elevated expression of DGAT2 in hybrid tilapia

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