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Dietary Alpha-Ketoglutarate Supplementation Improves Bone Growth, Phosphorus Digestion, and Growth Performance in Piglets

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成果类型:
期刊论文
作者:
Tian, Junquan;Yang, Fan;Bao, Xuetai;Jiang, Qian;Li, Yuying;...
通讯作者:
Jiang, Q.;Yao, K.
作者机构:
[Bao, Xuetai; Yang, Fan; Yao, Kang; Yin, Yulong; Jiang, Qian; Tian, Junquan] Chinese Acad Sci, Natl Engn Lab Pollut Control & Waste Utilizat Live, Lab Anim Nutr Physiol & Metab Proc, Key Lab Agroecol Proc Subtrop Reg,Inst Subtrop Agr, Changsha 410125, Peoples R China.
[Bao, Xuetai; Yang, Fan; Yao, Kang; Yin, Yulong; Tian, Junquan] Chinese Acad Sci, Univ Chinese Acad Sci, Inst Subtrop Agr, Beijing 100008, Peoples R China.
[Yin, Yulong; Jiang, Qian] Hunan Agr Univ, Coll Anim Sci & Technol, Changsha 410000, Peoples R China.
[Li, Yuying] Chinese Acad Agr Sci, Inst Bast Fiber Crops, Changsha 410205, Peoples R China.
通讯机构:
[Kang Yao; Qian Jiang] A
Authors to whom correspondence should be addressed.<&wdkj&>National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, Laboratory of Animal Nutritional Physiology and Metabolic Process, Key Laboratory of Agro-Ecological Processes in Subtropical Region, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha 410125, China<&wdkj&>College of Animal Science and Technology, Hunan Agricultural University, Changsha 410000, China<&wdkj&>Authors to whom correspondence should be addressed.<&wdkj&>National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, Laboratory of Animal Nutritional Physiology and Metabolic Process, Key Laboratory of Agro-Ecological Processes in Subtropical Region, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha 410125, China<&wdkj&>Institute of Subtropical Agriculture, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Beijing 100008, China
语种:
英文
关键词:
alpha-ketoglutarate;bone growth;apparent digestibility of phosphorus;piglets
期刊:
ANIMALS
ISSN:
2076-2615
年:
2023
卷:
13
期:
4
页码:
569-
基金类别:
Conceptualization, J.T., Q.J. and K.Y.; Methodology, X.B.; Software, J.T. and F.Y.; Validation, F.Y.; Formal analysis, J.T. and Y.L.; Investigation, J.T. and Y.L.; Resources, Y.Y. and K.Y.; Data curation, J.T. and K.Y.; Writing—original draft preparation, J.T.; Writing—review and editing, Q.J. and K.Y.; Visualization, F.Y.; supervision, Y.Y.; Project administration, Q.J., Y.Y. and K.Y.; Funding acquisition, K.Y. and Y.Y. All authors have read and agreed to the published version of the manuscript. This work was supported by the National Key R&D Plan of China (2021YFD1300400), the National Natural Science Foundation of China (32130099), the Key Programs of Frontier Scientific Research of the Chinese Academy of Sciences (QYZDY-SSW-SMC008), and the TaiShan Industrial Experts Program (tscy20190121).
机构署名:
本校为其他机构
院系归属:
动物科学技术学院
摘要:
Simple Summary Intensive farming in the modern pig industry has resulted in an increase in phosphorus pollution, which is a major environmental concern. The dietary intake of phosphorus is primarily employed for the growth and metabolism of pig bones. Dietary strategies to improve bone growth can be utilized to optimize the utilization of dietary phosphorus and reduce its release into the environment. Interestingly, recent studies have shown that alpha-ketoglutarate, an intermediate metabolite in the tricarboxylic acid cycle, improves osteogenesis in vitro. Therefore, we hypothesized that diet...

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