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The Regulatory Effect of Phytochemicals on Chronic Diseases by Targeting Nrf2-ARE Signaling Pathway

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成果类型:
期刊论文
作者:
He, Wen-Jiang;Lv, Cheng-Hao;Chen, Zhong;Shi, Meng;Zeng, Chao-Xi;...
通讯作者:
Si Qin
作者机构:
[Zeng, Chao-Xi; Qin, Si; Chen, Zhong; Shi, Meng; He, Wen-Jiang] Hunan Agr Univ, Coll Food Sci & Technol, Changsha 410128, Peoples R China.
[He, Wen-Jiang] Infinitus China Co Ltd, Guangzhou 510665, Peoples R China.
[Lv, Cheng-Hao; Qin, Si] Hunan Agr Univ, Coll Biol Sci & Technol, Changsha 410128, Peoples R China.
[Hou, De-Xing] Kagoshima Univ, Fac Agr, United Grad Sch Agr Sci, Kagoshima 8900065, Japan.
通讯机构:
[Si Qin] C
College of Food Science and Technology, Hunan Agricultural University, Changsha 410128, China<&wdkj&>College of Biological Science and Technology, Hunan Agricultural University, Changsha 410128, China<&wdkj&>Author to whom correspondence should be addressed.
语种:
英文
关键词:
phytochemicals;chronic disease;Nrf2-ARE pathway;chemoprevention
期刊:
Antioxidants
ISSN:
2076-3921
年:
2023
卷:
12
期:
2
页码:
236-
基金类别:
Conceptualization, W.-J.H., C.-H.L. and S.Q.; data curation, Z.C.; writing—original draft preparation, W.-J.H., C.-H.L. and Z.C.; writing—review and editing, D.-X.H., S.Q., M.S. and C.-X.Z.; supervision, D.-X.H. and S.Q.; project administration, S.Q.; funding acquisition, S.Q. All authors have read and agreed to the published version of the manuscript. This work was partially supported by the National Key Research and Development Program of China (2019YFC1604903) to Si Qin.
机构署名:
本校为第一机构
院系归属:
食品科学技术学院
生物科学技术学院
摘要:
Redox balance is essential to maintain the body’s normal metabolism. Once disrupted, it may lead to various chronic diseases, such as diabetes, neurodegenerative diseases, cardiovascular diseases, inflammatory diseases, cancer, aging, etc. Oxidative stress can cause or aggravate a series of pathological processes. Inhibition of oxidative stress and related pathological processes can help to ameliorate these chronic diseases, which have been found to be associated with Nrf2 activation. Nrf2 activation can not only regulate the expression of a s...

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